Depression, Depressionen

Figure_1

Symptomatic Outcomes

Figure 1 presents the HDRS₂₈ total score at the exit visit for each patient and the percent reduction in the average (two visits) baseline HDRS₂₈ in relation to the diagnosis for each patient (n 30). Overall, a 40% response rate was found using a 50% reduction in the baseline HDRS₂₈ total score to define response.

⁹There was no experimentation with alternative stimulation parameters to optimize efficacy during the stimulation adjustment period, since onset of improvement in depressive symptoms, when it occurred, typically took longer than the 2-week stimulation adjustment period permitted by the protocol.